Natural plant-based steroids originate from Smilax Sieboldii

Smilax Sieboldiiis a climbing shrub which mainly grows in East Asia, and South and North America [1]. Its young leaves are used for food and the subterranean parts have been used in Traditional Chinese Medicine (TCM) for arthritis, tumors and lumbago [2, 3]. This plant has aroused researches tremendous attention because of a natural steroidal sapogenin-laxogenin [4]. Laxogenin is a spirostanic analogue of brassinosteroid, shown to possess an anabolic/androgenic activity similar to one of the most efficient anabolic substances, anavar, yet without the side effects of liver toxicity or likelihood of testing positive for steroid [5].
5α-HydroxyLaxogenin, a homolog of laxogenin, is also a natural steroidsin green plant [5]. In the earliest time, both two plant-based steroids are sold in the market, while with the time being, consumers prefer to choose 5α-HydroxyLaxogenin. They strongly reflected that 5α-HydroxyLaxogenin had a better anabolic effect on their body than laxogenin, although the mechanism needs further studied.


What is Laxosterone®

Laxosterone® is the trademark of 5α-HydroxyLaxogenin from SYNMR BIOTECHNOLOGY (SHANGHAI)LIMITED. Due to very less content in nature plant, we create a green bioconversion method to get a highly purified 5α-HydroxyLaxogenin from nature plant materials. Meanwhile, we developed a new microencapsule5α-HydroxyLaxogenin, with very good bioavailability.

Highlight of Laxosterone®

However, its application was blocked by a surge of fake raw materials since 2010. We have tested different origins of 5α-Hydroxy Laxogenin from the market, content are all very low, only from 20-55%, even some are not 5-alpha Hydroxy Laxogenin at all.

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Benefits of Laxosterone®

According to a Russian research, 5α-Hydroxy Laxogenin could accelerate the gain of weight in rats by increasing the weight of the liver, heart, kidneys, musculus tibiliasis anterior and augmenting the total amount of protein therein as well. All of the above-mentioned changes become more pronounced with the study substance introduced to young animals [5].
Date also indicated that 5α-Hydroxy Laxogenin, used by athletes, produced dramatic strength increases in 3-5 days, and muscle mass increases in 3-4 weeks. The increase of protein synthesis by over 200% was the key to lean muscle growth and accelerated repair. Further investigation of the molecule showed that it could also balance cortisol response which is the major cornerstone for recovery and reduction of muscle wasting.

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